Olle Nygren Programme for Chemical Exposure Assessment NIWL

Olle Nygren

Associate professor, PhD

Postrodden 1997

Chemistry Department
Umeå University
Telephone: +4690 786 54 83
Mobil phone: +4670 66 36 706

Short CV

Education
BSc with chemistry, mathematics and statistics at Umeå University, 1983.
PhD in analytical chemistry at Umeå University, 1987.
Associate professor in analytical chemistry at Umeå University, 1996.

Main work

Development of sampling and selective analytical methods for drugs, organometallic compounds in the work environment and for biological monitoring as well as for assessment of exposure to drugs, metals and organometallic compounds in the work environment. Focus on simple and robust methods that can be used in the work places.
Teaching at the institute courses and at Umeå University.
Supervision of research students and student project works
Participate in national and international standardisation work in the field of chemical health hazards in the work environment

Current projects
Drug exposure. Assessment of drug exposure among medical staff during preparation and administration. This is a joint project with the Östra Hospital in Gothenburg, Swedish National Board for Occupational Safety and Health and the Katholishe University of Niemegen in Holland. *Latest publications: Moore, G and Nygren, O. Penicillin. Criteria document for Occupational Standards. Arbete & Hälsa, 2004:6, Arbetslivsinstitutet, Stockholm, 2004. Hedmer M, Jönsson B A, Nygren O. Development and validation of methods for environmental monitoring of cyclophosphamide in workplaces. J Environ Monit 6 (2004), 979-84. Nygren O, Gustavsson B, Eriksson R. A test method for assessment of spill and leakage from drug preparation systems, Ann Occup Hyg,* 49 (2005), 711 - 718. Nygren O. Development of measuring methods based on wipe sampling for assessment of emission and distribution of cytotoxic drugs in indoor environments. Proc 10th Intl Conf Indoor Air Quality and Climate, pp 2756-2761, 4-9th Sept, Beijing, China, 2005. Nygren O. Exposure to hazardous drugs. Hosp Parm Europe 4 (2006), 66-68. Nygren O, Olofsson E, Johansson L. Spill and leakage using a drug preparation system based on double filter technology. Ann Occup Hyg, submitted 2007.	Critical work task for drug leakage
Development of measurement methods for metals and organometals. Many metals occur in various forms with different toxicity. It is therefore essential to be able to selectively determine different forms of a metal for adequate assessment of its hazardous health effects. In this Ph D student project, different methods for speciation of metals are developed, e.g., speciation of hexavalent chromium in concrete and tanned leather, transferrin bound cobalt in blood, cisplatin in plasma. *Latest publications: Nygren O, Aspman O. Validation and application of wipe sampling and portable XRF analysis as an on-site screening method for assessment of deposited aerosols on workplaces, Aust J Chem* 37 (2004), 1021-28. Nygren O. Platinum element and gold. Occupational exposure. In Speciation anlysis of platinum group elements and gold, ed Cornelis R, Wiley & Son, London, 2005. Nygren O. Occupational exposure to palladium in various work environments. In Palladium Emissions in the Environment: Analytic, Environmental Assessment and Health Effects, eds Zereini F och Alt F, Springer Verlag, 2006. Nygren O. Wipe sampling as a tool for monitoring aerosol deposition in workplaces. J Environ Monit, 8 (2006), 49 - 52.	Welding work
Previous projects
Laser treatment. This project, which ended 1999, involved investigation of aerosol exposure during metal surface treatment with high power lasers. A possible continuation of this project is the development of methods for emission and exposure measurements during laser treatment of composite materials. The work has carried out in collaboration with Laser group at Luleå Technical University, ArgeLas in Wienna and Laser Zentrum Hannover. *Selection of publications:* Nygren O, Flinkfeldt J, Lidén G, Lundgren L, Püster T and Seebaum D. Emissions generated during laser cladding. Proc 3rd EUREKA Industrial Laser Safety Forum, pp 149-156, Copenhagen, 4-5 May, 1995. Haferkamp H, Püster T, Nygren O, Beck-Hansen E. Ring experiments as accompanying measure for investigations of emissions during laser material processing in the EU643 project. Proc 3rd EUREKA Industrial Laser Safety Forum, pp 123-130, Copenhagen, 4-5 May, 1995. Nygren O, Haferkamp H, Seebaum D, Püster T and Beck Hansen E. Round Robin experiments for comparison and evaluation of analytical methods for the determination of emissions from high-power laser material processing. Analyst 121 (1996), 1291-1294. Püster, T and Nygren, O. Gas and Fume Emissions, section 2 in "Laser Safety Handbook", Ed: Schröder, K, http://info.tuwien.ac.at/islt/safety/index.htm, Argelas, Wienna, Austria, 2002.	Laser welding Photo: Trumpf
Water Jet Cutting. The basis of this project, which ended during year 2000, has been the assessment of the occupational environment during abrasive water jet cutting in order to investigate the possibility to start a development project with the aim to improve the work environment. This project has been carried out in collaboration with the Water jet group at Luleå Technical University and with funding from the Swedish Council for Work Life Research. *Publication:* Nygren O, Flinkfeldt J. Förbättrad arbetsmiljö vid abrasiv vattenskärning (in Swe) [Improved work environment during abrasive water-jet cutting] Arbetslivsrapport 2000:7, Arbetslivsinstitutet, Solna, 2000.	Aersol sampling during water jet cutting Photo: O Nygren

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This page was updated: 2007-09-16